RCPA Haematology interactive diagrams

Haematopoiesis lineage tree + Primary haemostasis — platelet plug + Fibrinolysis & D-dimer — Understand normal anatomy, physiology, biochemistry and molecular biology of the haematopoietic, lymphatic, vascular, reticuloendothelial and coagulation systems.

Complement cascade & hypersensitivity I–IV + Amyloid typing + Haematopoiesis lineage tree + Anaemia classification + White cell maturation & left shift — Understand the mechanisms and pathophysiology of haematological and related conditions including how they are diagnosed and monitored in the laboratory.

Iron homeostasis + Anaemia classification — Understand the principles and techniques for serum iron, total iron binding capacity, soluble transferrin receptor studies and ferritin measurements.

Anaemia classification + Haemoglobin variants & electrophoresis — Understand the principles and techniques for full blood count indices using an automated haematology analyser.

Anaemia classification — Understand the principles and techniques for the reticulocyte count, both manual and automated.

Haemolysis — intravascular vs extravascular — Understand the principles and techniques for examination of urine for haemosiderin.

Haemolysis — intravascular vs extravascular — Understand the principles and techniques for tests for red cell membrane disorders, including flow cytometry.

Haemolysis — intravascular vs extravascular — Understand the principles and techniques for cold agglutinin titre, thermal amplitude and i/I specificity.

Haemolysis — intravascular vs extravascular — Understand the principles and techniques for plasma haptoglobin measurement.

Blood groups & transfusion compatibility — Demonstrate competence in blood grouping, antibody screening and antibody identification, red cell phenotyping, manual crossmatch, and selection of appropriate red cell products for transfusion.

Blood groups & transfusion compatibility — Understand blood grouping and antibody screening by manual, semi-automated and automated techniques.

Blood groups & transfusion compatibility — Understand antibody detection, identification and titre.

Blood groups & transfusion compatibility — Understand cross-matching procedures.

Blood groups & transfusion compatibility — Understand antenatal serology.

Blood groups & transfusion compatibility — Understand the investigation and management of transfusion reactions.

Blood film morphology identify-drill + White cell maturation & left shift — Understand the principles and techniques of preparation of blood films.

Granulomatous inflammation + Haematopoiesis lineage tree — Understand the principles and techniques of preparation of bone marrow aspirate films.

Iron homeostasis — Understand the principles and techniques of staining of blood and bone marrow for iron.

Blood film morphology identify-drill — Understand the principles and techniques of differential count on blood and bone marrow aspirate films.

Primary haemostasis — platelet plug — Understand the principles and clinical utility of platelet function and aggregation analysers.

Haemoglobin variants & electrophoresis — Understand the principles and clinical utility of electrophoresis and capillary electrophoresis.

Flow cytometry — gating & blast immunophenotyping — Understand the principles and clinical utility of flow cytometry technologies.

Blood film morphology identify-drill — Understand the principles and clinical utility of digital imaging of cell morphology.

Flow cytometry — gating & blast immunophenotyping + White cell maturation & left shift — Understand the principles and techniques used in the flow cytometric assessment of leukaemia.

Flow cytometry — gating & blast immunophenotyping — Understand the principles and techniques used in the flow cytometric assessment of lymphoproliferative disorders.

Iron homeostasis — Understand hereditary haemochromatosis and secondary iron overload: HFE gene mutations (C282Y homozygosity, C282Y/H63D compound heterozygosity) and non-HFE causes (TFR2, HJV, HAMP, SLC40A1); biochemical and MRI-based ass…

Coagulation screen interpreter + Coagulation cascade + Fibrinolysis & D-dimer — Understand the principles and techniques of prothrombin time and international normalised ratio assays.

Coagulation screen interpreter + Coagulation cascade — Understand the principles and techniques of activated partial thromboplastin time assays.

Coagulation screen interpreter + Coagulation cascade — Understand the principles and techniques of thrombin time, reptilase and fibrinogen assays.

Coagulation screen interpreter + Coagulation cascade — Understand the principles and techniques of clotting factor assays for factors II, V, VIII, IX, X, XI and XII.

Coagulation screen interpreter + TTP / HUS / DIC / HIT discriminator — Understand the principles and techniques of coagulation factor inhibitor assessment (e.g. Bethesda assay).

Coagulation screen interpreter + TTP / HUS / DIC / HIT discriminator + Fibrinolysis & D-dimer — Understand the principles and techniques of assays of fibrin and fibrinogen degradation products (e.g. D-Dimer).

Thrombocytopenia differential tree + Primary haemostasis — platelet plug — Understand the principles and techniques of platelet aggregation studies.

Coagulation cascade — Understand the principles and techniques of protein C, protein S and antithrombin assays.

TTP / HUS / DIC / HIT discriminator + Coagulation cascade — Understand the principles and techniques for tests for heparin-associated thrombocytopenia.

Coagulation screen interpreter + Coagulation cascade — Interpret the effects of anticoagulants on coagulation tests.